The influence of muscle interstitial volume on K+-induced heart rate drive in rats

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Deutscher übersetzter Titel:Einfluss des interstitiellen Volumens im Muskel auf den durch Kalium verursachten Herzfrequenzantrieb bei Ratten
Autor:Baum, K.; Essfeld, D.; Stegemann, J.
Erschienen in:European journal of applied physiology
Veröffentlicht:57 (1988), 1, S. 33-38, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:1439-6319, 0301-5548
DOI:10.1007/BF00691234
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Erfassungsnummer:PU198803032502
Quelle:BISp

Abstract des Autors

During exercise heart rate is influenced by reflexogenic drives which are elicited by receptors situated in the interstitial space. Since the structure of intersitial tissue is complex (e.g. fixed negative charges of glycosaminoglycans), the situation in the immediate surrounding of the receptors might differ from the free fluid phases of blood or lymph in which the concentrations of stimulating substances are usually determined. Physiological variations of the interstitial structure may be due to changes in interstitial volume induced by exercise or the hydrostatic effects on body fluids. The objective of the present study was to investigate the effect of the interstitial volume on the relationship between heart rate and K+ stimuli applied through the muscle blood vessels.