Abstract

The purpose of this study was to investigate the variations of HDLCholesterol (HDL-C) and serum lipids, related to menstrual cycles in human females. Four healthy adult females volunteered to participate in this experiment, HDL-C, total cholesterol (T-C), serum triglyceride (STG) and lipoprotein fractions (by cephalose electrophoresis) were determined of 2 to 3 cycles per one female. Blood sampling was done after 12-h fasting 2 days a week. Two females showed higher HDL-C/T ratio in luteal phase compared to folicular phase every cycles. Other two females showed the same tendency although not in all cycles. The values of STG were lower in luteal phase, corresponding the changes of HDL-C/T-C ratio. A significant positive relation between HDL-C concentration and HDL-C/T-C ratio, and a significant negative relation between STG or T-C and the HDL-C/T-C ration were observed in the samples of the same subjects. From these results it is shown that relatively higher ratio of HDL-C/T-C in luteal phase may be related to the relatively lower concentration of STG and or T-C and higher HDL-C in the same phase, in human female subjects. Verf.-Referat