Exercise stress testing : correlations among history of angina, ST-segment response and prevalence of coronary-artery disease in the Coronary Artery Surgery Study
Deutscher übersetzter Titel: | Belastungstest : Beziehungen zwischen Verlauf der Angina pectoris, ST-Segment-Reaktion und Vorherrschen der Koronararterienerkrankung in der Koronararterien-Chirurgie-Studie |
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Autor: | Weiner, D.A.; Ryan, T.J.; McCabe, C.H.; Kennedy, J.W.; Schloss, M.; Tristani, F.; Chaitman, B.R.; Fisher, L.D. |
Erschienen in: | The New England journal of medicine |
Veröffentlicht: | 301 (1979), S. 230-235, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0028-4793, 1533-4406 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU198003010992 |
Quelle: | BISp |
Abstract
To determine to what extent the diagnostic accuracy of stress testing is influenced by the prevalence of coronary-artery disease, we correlated the description of chest pain, the result of stress testing and the results of coronary arteriography in 1465 men and 580 women from a multicentered clinical trial. The pre-test risk (prevalence of coronary-artery disease) varied from 7 to 87 per cent, depending on sex and classification of chest pain. A positive stress test increased the pre-test risk by only 6 to 20 per cent whereas a negative test decreased the risk by only 2 to 28 per cent. Although the percentage of false-positive results differed between men and women (12+/- 1 per cent versus 53+/-3 per cent), this difference was not seen in a subgroup matched for prevalence of coronary-artery disease. We conclude that the ability of stress testing to predict coronary-artery disease is limited in a heterogeneous population in which the prevalence of disease can be estimated through classification of chest pain and the sex of the patient. Verf.-Referat