A prospective cohort study of acute kidney injury in multi-stage ultramarathon runners : the Biochemistry in Endurance Runner Study (BIERS)
Gespeichert in:
| Deutscher übersetzter Titel: | Eine prospektive Kohortenstudie zu akuten Nierenverletzungen bei Läufern in Ultramarathon-Etappenrennen : Studie zur Biochemie von Ausdauerläufern (BIERS) |
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| Autor: | Lipman, Grant S.; Krabak, Brian J.; Waite, Brandee L.; Logan, Sarah B.; Menon, Anil; Chan, Garrett K. |
| Erschienen in: | Research in sports medicine |
| Veröffentlicht: | 22 (2014), 2, S. 185-192, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 1543-8627, 1543-8635 |
| DOI: | 10.1080/15438627.2014.881824 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201501000818 |
| Quelle: | BISp |
Abstract des Autors
The purpose of the study was to evaluate the prevalence of acute kidney injury (AKI) during a multi-stage ultramarathon foot race. A prospective observational study was taken during the Gobi 2008; Sahara 2008; and Namibia 2009 RacingThePlanet 7-day, 6-stage, 150-mile foot ultramarathons. Blood was analyzed before, and immediately after stage 1 (25 miles), 3 (75 miles), and 5 (140 miles). Creatinine (Cr), glomerular filtration rate (GFR), and incidence of AKI were calculated and defined by RIFLE criteria. Thirty participants (76 percent male, mean age 40 + 11 years) were enrolled. There were significant declines in GFR after each stage compared with the pre-race baseline (p < 0.001), with the majority of participants (55-80 percent) incurring AKI. The majority of study participants encountered significant renal impairment; however, no apparent cumulative effect was observed, with resolution of renal function to near baseline levels between stages. Verf.-Referat