Abstract des Autors

After describing the universal and biological aspects of evolution experimental investigations regarding cerebral blood flow and the behaviour of neurotransmitters during ergometer exercise are depicted. During bicycle exercise a global increase of cerebral blood flow was found by about 15% at a work load level of 25 Watt and by about 25% at 100 Watt. The increase of blood flow was greater in the grey than in the white matter. An increased blood pressure as well as an increased neuronal activity are respected to be possible causes. It is teleologically discussed whether biochemical substances additionally released by the nervous system during physical exercise have to fulfil peripheral tasks. In this connection, the behaviour of endogenous opioide peptides and of their exercise-induced influence on pain sensitivity and pain tolerance is explained. "Jogger's high" is discussed as well as the hypothesis that so-called "sports withdrawal symptoms" after abrupt discontinuation of years of performance training may be caused by different levels of endogenous opiates. In this connection, the silent myocardial ischemia is looked at. Hemodynamic and metabolic effects of serotonine blockade and of dopamine agonism during differently dosed ergometer exercise are described. Finally, a hypothetical connection between psychic behaviour and cardiac reactions as result of neurotransmitters is assumed. Verf.-Referat