Abstract des Autors

10 female and 15 male sport students trained one leg on a bicycle ergometer. Training lasted 6 weeks with 4 sessions weekly. The subject were divided in an "aerobic" and an "anaerobic" (> the 4 mmol threshold) group. In muscle biopsies taken from the M. vastus lateralis before and after training, the activities of the following enzymes were determined: pyruvatekinase (PK), lactate-dehydrogenase (LDH), malate-dehydrogenase (MDH) and cytochrome c oxydase (COx). Comparing the groups, no differences in activity changes were found. But within the groups we could divide into subjects showing increases in MDH and COx activities and subjects who showed definite decreases. In this regard reaction of COx was much more striking. The decreases of enzyme activities are supposed to indicate a functional overload. Verf.-Referat