Abstract

An intramuscular administration of 2 IU of human growth hormone (hGH) to 6 untrained persons caused a rapid increase of its concentration in blood, followed by an augmented insulin level, and a slight hyperglycemia, and a reduced level of free fatty acids. When a 2 h bicycle exercise was performed at 60 of VO2max after hGH injection, there was no initial lag period in the rise of hGH concentration and its peak values exceeded those during the exercise after placebo administration. Administration of hGH produced a less pronounced hypoglycemia at the beginning of exercise, but no differences in the dynamics of insulin and lipids in blood were observed. It was concluded that during exercise growth hormone exerts a supporting effect on blood glucose homeostasis but not on lipolysis. Verf.-Referat