Abstract

Until 20 years ago, the physical phenomenon of bubbling was the primary consideration in decompression sickness (DCS). Now the physiological aspects of DCS and the physiochemical states that lead to bubbling are better understood. This paper discusses four important developments in the study of DCS: (1) the recognition of the importance of hydration states and flow in the microcirculation, (2) the documentation of intravascular bubble formation during asymptomatic decompressions, (3) the recognition of pharmacological substances that influence DCS, and (4) the development of an animal model to understand spinal cord bends. More attention will probably be given to the use of pharmacological agents in treating DCS in the future. Verf.-Referat