Quality of life after coronary bypass: a multicentre study of routinely collected health data in the Netherlands

Author: Blokzijl, Fredrike; Houterman, Saskia; van Straten, Bart H M; Daeter, Edgar; Brandon Bravo Bruinsma, George J; Dieperink, Willem; Reneman, Michiel F; Keus, Frederik; van der Horst, Iwan C C; Mariani, Massimo A
Language: English
Published: 2019
Source: PubMed Central (PMC)
Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735900/
Identification number: ftpubmed:oai:pubmedcentral.nih.gov:6735900


OBJECTIVES: In this study, our aim was to explore how coronary artery bypass grafting affects quality of life, and how this varies with age, particularly with patients at risk of deterioration. METHODS: In a retrospective, multicentre cohort study, patients with isolated coronary artery bypass grafting and electively operated between January 2011 and January 2015 with pre- and postoperative quality-of-life data were included. Patients were classified into 3 age groups: <65, 65–79 and ≥80 years. Quality of life was measured up to 1-year follow-up using the Short Form-12 or the Short Form-36 health survey. A multivariable, linear regression analysis, with an adjustment for confounders, was used to evaluate the association between age and quality of life. RESULTS: A total of 2606 patients were included in this study. Upon one-year of follow-up, the mean physical health of patients increased from 54 at baseline to 68, and mental health increased from 60 to 67. We observed decreased mental health in 20% of patients aged <65 years, 20% of patients aged 65–79 years and 29% of patients aged ≥80 years (P = 0.039). In this study, age was not associated with a lower physical or mental component score (P = 0.054 and P = 0.13, respectively). Independent risk factors for a decrease in quality of life consist of a better physical and mental score at baseline (P < 0.001) and a reduced left ventricular function (P < 0.001). CONCLUSIONS: Most patients experience a relevant increase in physical and mental quality of life, but a proportion of patients aged ≥80 years undergo significant deterioration in mental health.