Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans

Autor: Vogiatzis, I.; Zakynthinos, S.; Georgiadou, O.; Golemati, S.; Pedotti, A.; Macklem, P. T.; Roussos, C.; Aliverti, A.
Sprache: Englisch
Veröffentlicht: 2006
Quelle: PubMed Central (PMC)
Online Zugang: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782100
http://www.ncbi.nlm.nih.gov/pubmed/17149607
http://dx.doi.org/10.1007/s00421-006-0342-2
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782100
https://doi.org/10.1007/s00421-006-0342-2
Erfassungsnummer: ftpubmed:oai:pubmedcentral.nih.gov:1782100
id ftpubmed:oai:pubmedcentral.nih.gov:1782100
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recordtype bispbase
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782100
http://www.ncbi.nlm.nih.gov/pubmed/17149607
http://dx.doi.org/10.1007/s00421-006-0342-2
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782100
https://doi.org/10.1007/s00421-006-0342-2
url-type primary
primary
primary
pmc
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publishDate 2006
publishDate_facet 2006
baseCollectionName PubMed Central (PMC)
baseCountry us
title Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans
spellingShingle Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans
title_short Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans
title_sort Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans
spelling Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans
author2 Vogiatzis, I.
Zakynthinos, S.
Georgiadou, O.
Golemati, S.
Pedotti, A.
Macklem, P. T.
Roussos, C.
Aliverti, A.
author_facet Vogiatzis, I.
Zakynthinos, S.
Georgiadou, O.
Golemati, S.
Pedotti, A.
Macklem, P. T.
Roussos, C.
Aliverti, A.
author2-role Autor
Autor
Autor
Autor
Autor
Autor
Autor
Autor
abstract In healthy subjects expiratory flow limitation (EFL) during exercise can lower O2 delivery to the working muscles. We hypothesized that if this affects exercise performance it should influence O2 kinetics at the end of exercise when the O2 debt is repaid. We performed an incremental exercise test on six healthy males with a Starling resistor in the expiratory line limiting expiratory flow to ∼ 1 l s−1 to determine maximal EFL exercise workload (Wmax). In two more square-wave exercise runs subjects exercised with and without EFL at Wmax for 6 min, while measuring arterial O2 saturation (% SaO2), end-tidal pressure of CO2 (PETCO2) and breath-by-breath O2 consumption \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${({\dot{V}}\hbox{O}_{2})}$$\end{document} taking into account changes in O2 stored in the lungs. Over the last minute of EFL exercise, mean PETCO2 (54.7 ± 9.9 mmHg) was significantly higher (P < 0.05) compared to control (41.4 ± 3.9 mmHg). At the end of EFL exercise %SaO2 fell significantly by 4 ± 3%. When exercise stopped, EFL was removed, and we continued to measure \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{\dot{V}}\hbox{O}_{2}.}$$\end{document} During recovery, there was an immediate step increase in \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{\dot{V}}\hbox{O}_{2},}$$\end{document} so that repayment of EFL O2 debt started at a higher \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} ...
abstract_type general
abstract_lang eng
language eng
publisher Springer-Verlag
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