Optical coherence tomography in diagnosis of early primary open angle glaucoma

Author: Ou Hai; Li Guo; Chun-Xia Guo; Zhi-Li Cui
Language: English
Published: 2018
Source: Directory of Open Access Journals: DOAJ Articles
Online Access: http://ies.ijo.cn/cn_publish/2018/5/201805035.pdf
https://doaj.org/toc/1672-5123
https://doaj.org/toc/1672-5123
https://doi.org/10.3980/j.issn.1672-5123.2018.5.35
https://doaj.org/article/9024ad6f25e6441dad13897760964d64
Identification number: ftdoajarticles:oai:doaj.org/article:9024ad6f25e6441dad13897760964d64

Summary

AIM: To evaluate the clinical value of retinal nerve fiber layer(RNFL)thickness, optic disc parameters and macular thickness by optical coherence tomography(OCT)in early diagnosis of primary open angle glaucoma(POAG). METHODS: Sixty-five patients(eighty-five eyes)were selected as a study group and fifty-two normal people(seventy-eight eyes)were selected as a control group. The retinal nerve fiber layer thickness, optic disc parameters, including cup/disc(C/D)rate, cup area(CA), cup volume(CV), disc area(DA), rim area(RA)and rim volume(RV), and macular thickness were detected by Cirrus HD-OCT. The data were compared and analyzed. RESULTS: The retinal nerve fiber layer thickness of superior, inferior, temple, nasal and average in the study group were all significantly thinner than those of the control group( P <0.001). The cup area, cup volume and cup/disc ratio in the study group were significantly higher than those of the control group( P <0.001); while the rim area and rim volume in the study group were significantly lower than those of the control group( P <0.001). But the disc area was not significantly different between two groups( P >0.05). The macular thickness of superior, inferior, temple and nasal in the study group were all significantly thinner than those of the control group( P <0.001). CONCLUSION: OCT can detect the change of retinal nerve fiber layer thickness, optic disc parameters and macular thickness, it is helpful for early diagnosis of POAG.