Zusammenfassung

The purpose of this paper was to determine the effect of replacing breakfast with a high-fat drink on fat mass (FM), lean mass (LM), percent body fat (), visceral fat (VAT), resting metabolic rate (RMR), fuel utilization (RER), blood lipids and satiety in overweight and obese adults. Healthy adults ( n = 42; 21 Females; body mass index (BMI): 32.8 ± 4.6 kg·m −2 ) were randomized to control (CON; n = 21) or meal replacement (MRP; n = 22) groups. Body composition was measured using a four-compartment model; RMR and RER were assessed from indirect calorimetry. The MRP (70% fat) was consumed once daily for eight weeks. For males, there was no change ( p > 0.05) in FM (mean difference (MD) = 0.41 ± 1.19 kg], MD = 0.50 ± 1.09%, LM MD = −0.64 ± 1.79 kg, or VAT MD = −0.31 ± 1.36 cm for MRP versus CON. Similarly, no differences for females for FM MD = −0.73 ± 1.37 kg, MD = −0.57 ± 1.26%, LM MD = 0.31 ± 1.37 kg, or VAT MD: −0.83 ± 1.2 cm. HDL was significantly reduced in the MRP group for females (adjusted mean change: −6.41 ± 4.44 units, p = 0.018). There was no effect on RMR or RER. Satiety increased in the afternoon for MRP ( p = 0.021). Despite high fat, no negative impact on lipids resulted; increased satiety may be beneficial for controlling afternoon cravings, but does not affect body composition.