Differences in pain intensity in anti- and pro-nociceptive pain profile subgroups in patients with knee osteoarthritis
Gespeichert in:
| Deutscher übersetzter Titel: | Unterschiede in der Schmerzintensität in Untergruppen des anti-nociceptiven und pro-nociceptiven Schmerzprofils bei Patienten mit Knie-Osteoarthritis |
|---|---|
| Autor: | Boßmann, Tanja; Brauner, Torsten; Horstmann, Thomas |
| Erschienen in: | Pain management |
| Veröffentlicht: | 8 (2018), 1, S. 27-36, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 1758-1877, 1758-1869 |
| DOI: | 10.2217/pmt-2017-0039 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU202011010860 |
| Quelle: | BISp |
Abstract des Autors
Aim: Facilitated temporal summation is one component of central sensitization. The aim of this exploratory study was to classify pro-, eu- and antinociceptive subgroups based on wind-up ratio cut-off scores in patients with knee osteoarthritis (OA). Patients & methods: A total of 56 patients with knee OA met the inclusion criteria. Temporal summation was measured and wind-up ratio was calculated. Reference values of 180 healthy subjects were used to define wind-up ratio cut-off scores. Results: Twenty-seven percent of patients showed a pro-nociceptive pain profile. Sixteen percent of patients showed an anti-nociceptive pain profile. A eu-nociceptive pain profile was present in 57% of patients. Conclusion: Central pain sensitization was present in approximately a third of knee OA patients. The results should be confirmed in larger studies.