Impact of sedentary time on chronic kidney disease and disability incidence in community-dwelling Japanese older adults : a 4-year prospective cohort study

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Deutscher übersetzter Titel:Auswirkung der sitzend verbrachten Zeit auf chronische Nierenerkrankungen und das Auftreten von Gebrechen bei selbstständig lebenden älteren Japanern : eine prospektive Kohortenstudie über vier Jahre
Autor:Lee, Sungchul; Lee, Sangyoon; Bae, Seongryu; Harada, Kazuhiro; Jung, Songee; Makino, Keitaro; Shimada, Hiroyuki
Erschienen in:Journal of aging and physical activity
Veröffentlicht:27 (2019), 2, S. 184-190, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Elektronische Ressource (online) Gedruckte Ressource
Sprache:Englisch
ISSN:1063-8652, 1543-267X
DOI:10.1123/japa.2017-0326
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Erfassungsnummer:PU201904002692
Quelle:BISp

Abstract des Autors

This study examined the association between the estimated glomerular filtration rate (eGFR) and disability incidence according to sedentary time in community-dwelling Japanese older adults. This prospective cohort study sampled 5,104 community-dwelling older adults (≥65 years) enrolled in a health promotion study in a general population. The participants (n = 4,457; ≥65 years) were monitored for inclusion in the long-term care insurance system for 4 years. This study used blood samples to assess eGFR. Cox proportional regression analysis was used to determine predictors of disability. In total, 461 participants (10.3%) became newly certified as needing long-term care insurance services. Cox regression models were adjusted for multiple confounders: eGFR < 45 ml/min/1.73 m2 (hazard ratio = 1.741, 95% confidence interval [1.193–2.539]) and eGFR < 45 ml/min/1.73 m2 with high sedentary time (≥8 hr) (hazard ratio = 4.367, 95% confidence interval [2.021–9.438]) remained significantly associated with disability incidence. Our findings suggest that in the case of chronic kidney disease, the disability incidence rate may be affected by sedentary time.