Exercise increases the dynamics of diurnal cortisol secretion and executive function in people with amnestic mild cognitive impairment
Gespeichert in:
| Deutscher übersetzter Titel: | Körperliches Training erhöht bei Personen mit leichter kognitiver Störung die Dynamik der täglichen Kortisolausschüttung und der ausführenden Funktion |
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| Autor: | Tortosa-Martínez, Juan; Clow, Angela; Caus-Pertegaz, Nuria; González-Caballero, Gloria; Abellán-Miralles, Immaculada; José Saenz, María |
| Erschienen in: | Journal of aging and physical activity |
| Veröffentlicht: | 23 (2015), 4, S. 550-558, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 1063-8652, 1543-267X |
| DOI: | 10.1123/japa.2014-0006 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201603001211 |
| Quelle: | BISp |
Abstract des Autors
Regular physical activity is protective against, and beneficial for, mild cognitive impairment (MCI), dementia, and Alzheimer´s disease. The mechanisms underlying these benefits remain unknown although it has been suggested that exercise-induced changes in the circadian pattern of cortisol secretion may be implicated. Fitness, salivary cortisol levels (0 and 30 min postawakening, midday, 5 p.m., and 9 p.m.), and cognitive function were determined in a group of amnestic MCI patients (n = 39) before and after a three-month exercise program (n = 19) or usual care (n = 20). At baseline, fitness measures were positively correlated with peak levels of cortisol and a greater fall in cortisol concentration from peak levels to midday. The exercise intervention successfully increased fitness and resulted in a greater fall in cortisol concentration from peak to midday, compared with the control group. The exercise intervention enhanced indices of executive function, although memory, mood, and functionality were not affected.