Left ventricular untwisting in athlete’s heart : key role in early diastolic filling?
Deutscher übersetzter Titel: | Linksventrikuläre Entspannung beim Sportlerherz : Schlüsselrolle bei der frühen diastolischen Füllung? |
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Autor: | Kovács, Attila; Apor, A.; Nagy, A.; Vágó, H.; Tóth, A.; Nagy, A.I.; Kováts, T.; Sax, B.; Széplaki, G.; Becker, D.; Merkely, B. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 35 (2014), 3, S. 259-264, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-0033-1349076 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201405004437 |
Quelle: | BISp |
Abstract
Untwisting contributes to left ventricular filling through suction generation. We sought to investigate diastolic function and untwisting dynamics in different forms of left ventricular hypertrophy: in athlete’s heart and hypertrophic cardiomyopathy. Elite athletes in kayaking, canoeing and rowing (n=28), patients with hypertrophic cardiomyopathy (HCM, n=15) and healthy sedentary volunteers (n=13) were compared. Left ventricular volumes, wall thickness-to-volume ratio were assessed by cardiac MRI. Following conventional and tissue Doppler measurements, untwist and untwist rate were determined by speckle tracking echocardiography. Wall thickness-to-volume ratio describing remodelling was significantly higher in HCM, but similar in athletes and controls (athlete vs. HCM vs. control: 0.107±0.019 vs. 0.271±0.091 vs. 0.104±0.012 mm×m²/ml, mean±SD, p<0.001). Mitral lateral annulus e’ velocity referred to diastolic dysfunction in HCM (15.3±3.6 vs. 7.9±3.3 vs. 15.0±3.0 cm/s, p<0.01). At time point of mitral valve opening, untwist and untwist rate were significantly different: the highest values were measured in athletes, while the lowest were found in HCM (untwist: 51.3±19.1 vs. 11.6±10.4 vs. 35.9±16.3%; untwist rate: −32.5±13.0 vs. −10.6±10.8 vs. −23.0±7.7°/s, p<0.05). Untwisting correlated with E/A, e’ and E/e’. Athlete’s heart is characterized by increased untwist and untwist rate, which can aid diastolic function. Evaluation of untwisting dynamics may help to distinguish pathological hypertrophy. Verf.-Referat