Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport
Gespeichert in:
| Deutscher übersetzter Titel: | Nachweis von EPO- und Blutdoping : das hämatologische Modul des biologischen Passes für Sportler |
|---|---|
| Autor: | Schumacher, Yorck Olaf; Saugy, Martial; Pottgießer, Torben; Robinson, Neil |
| Erschienen in: | Drug testing and analysis |
| Veröffentlicht: | 4 (2012), 11 (Sports drug testing for erythropoiesis-stimulating agents and autologous blood transfusion), S. 846-853, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
| Sprache: | Englisch |
| ISSN: | 1942-7603, 1942-7611 |
| DOI: | 10.1002/dta.406 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201301000604 |
| Quelle: | BISp |
| id |
PU201301000604 |
|---|---|
| bisp-collection |
db |
| format |
Literatur |
| last_indexed |
2022-08-19T09:37:55Z |
| first_indexed |
2013-01-23T15:01:08Z |
| publication_source |
BISp |
| subformat |
Zeitschriftenartikel |
| hierarchy_top_id |
JO00000100376 |
| hierarchy_parent_id |
JOI201200110100376 |
| hierarchy_top_title |
Drug testing and analysis |
| hierarchy_parent_title |
Drug testing and analysis, 2012, 11 |
| is_hierarchy_id |
PU201301000604 |
| is_hierarchy_title |
Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport |
| hierarchy_sequence |
0846 |
| recordtype |
bisparticle |
| publishDate |
2012 |
| publishDate_facet |
2012 |
| language |
eng |
| title |
Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport |
| spellingShingle |
Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport Biochemie Biologie Blutbild Blutdoping Bluttransfusion Doping Dopingbekämpfung Dopingnachweis Erythropoese Erythropoetin Hämatologie Sportler |
| title_sort |
detection of epo doping and blood doping the haematological module of the athlete biological passport |
| title_short |
Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport |
| title_alt |
Nachweis von EPO- und Blutdoping : das hämatologische Modul des biologischen Passes für Sportler |
| title_alt_lang |
deu |
| media_type |
Gedruckte Ressource Elektronische Ressource (online) |
| city |
Chichester |
| abstract |
The increase of the body's capacity to transport oxygen is a prime target for doping athletes in all endurance sports. For this pupose, blood transfusions or erythropoiesis stimulating agents (ESA), such as erythropoietin, NESP, and CERA are used. As direct detection of such manipulations is difficult, biomarkers that are connected to the haematopoietic system (haemoglobin concentration, reticulocytes) are monitored over time (Athlete Biological Passport (ABP)) and analyzed using mathematical models to identify patterns suspicious of doping. With this information, athletes can either be sanctioned directly based on their profile or targeted with conventional doping tests. Key issues for the appropriate use of the ABP are correct targeting and use of all available information (e.g. whereabouts, cross sectional population data) in a forensic manner. Future developments of the passport include the correction of all concentration-based variables for shifts in plasma volume, which might considerably increase sensitivity. New passport markers from the genomic, proteomic, and metabolomic level might add further information, but need to be validated before integration into the passport procedure. A first assessment of blood data of federations that have implemented the passport show encouraging signs of a decreased blood-doping prevalence in their athletes, which adds scientific credibility to this innovative concept in the fight against ESA- and blood doping. Verf.-Referat |
| abstract_lang |
eng |
| abstract_type |
abstract |
| author2 |
Schumacher, Yorck Olaf Saugy, Martial Pottgießer, Torben Robinson, Neil |
| author_facet |
Schumacher, Yorck Olaf Saugy, Martial Pottgießer, Torben Robinson, Neil |
| author2-role |
Autor Autor Autor Autor |
| author2-authorityid |
P113912 |
| author_author_facet |
Schumacher, Yorck Olaf Saugy, Martial Pottgießer, Torben Robinson, Neil |
| author2-synonym |
Schumacher, Y.O. ,Schumacher, York Olaf ,Schumacher, York-Olaf ,Schumacher, Yorck-Olaf ,Schumacher, Yorck O. |
| author2_hierarchy_facet |
0/Autor/ 1/Autor/Schumacher, Yorck Olaf/ 0/Autor/ 1/Autor/Saugy, Martial/ 0/Autor/ 1/Autor/Pottgießer, Torben/ 0/Autor/ 1/Autor/Robinson, Neil/ |
| doi |
10.1002/dta.406 |
| spelling |
10.1002/dta.406 1942-7603 1942-7611 2462336-2 Biochemie Biologie Blutbild Blutdoping Bluttransfusion Doping Dopingbekämpfung Dopingnachweis Erythropoese Erythropoetin Hämatologie Sportler athlete biochemistry biology blood doping blood picture blood transfusion doping doping detection erythropoiesis erythropoietin fight against doping hematology Sportbiologie Athlet Profisportler Dopingmittel Dopinganalyse EPO Eigenblutinfusion Eigenblutreinfusion sportsman autologous blood hemogram Detection of EPO doping and blood doping : the haematological module of the Athlete Biological Passport PU201301000604 201301000604 |
| url |
https://dx.doi.org/10.1002/dta.406 |
| url-type |
fulltext |
| url-free |
1 |
| free_access |
1 |
| issn |
1942-7603 1942-7611 |
| zdb |
2462336-2 |
| location_hierarchy_facet |
0/Großbritannien/ 1/Großbritannien/England/ |
| topic |
Biochemie Biologie Blutbild Blutdoping Bluttransfusion Doping Dopingbekämpfung Dopingnachweis Erythropoese Erythropoetin Hämatologie Sportler |
| topic_facet |
Biochemie Biologie Blutbild Blutdoping Bluttransfusion Doping Dopingbekämpfung Dopingnachweis Erythropoese Erythropoetin Hämatologie Sportler |
| topic_en |
athlete biochemistry biology blood doping blood picture blood transfusion doping doping detection erythropoiesis erythropoietin fight against doping hematology |
| topic_en_facet |
athlete biochemistry biology blood doping blood picture blood transfusion doping doping detection erythropoiesis erythropoietin fight against doping hematology |
| synonym |
Sportbiologie Athlet Profisportler Dopingmittel Dopinganalyse EPO Eigenblutinfusion Eigenblutreinfusion |
| synonym_en |
sportsman autologous blood hemogram |
| journal_facet |
Drug testing and analysis |
| container_title |
Drug testing and analysis |
| container_volume |
4 |
| container_issue |
11 |
| container_start_page |
S. 846-853 |
| container_special_issue |
Sports drug testing for erythropoiesis-stimulating agents and autologous blood transfusion |
| has_references |
1 |
| institution |
BISp |
| journal_fac |
JO00000100376 |
| journal_year |
2012 |
| journal_issue |
11 |
| _version_ |
1797309808663068672 |
| score |
12,71233 |