Degradation of endogenous steroids by microorganisms
| Deutscher übersetzter Titel: | Der Abbau von endogenen Steroidprofilen durch Mikroorganismen |
|---|---|
| Autor: | Liu, Xin; Xing, Yanyi; Xu, Youxuan; Yang, Zhiyong; Wu, Moutian |
| Erschienen in: | Recent advances in doping analysis (19) : Proceedings of the Manfred-Donike-Workshop ; 29th Cologne Workshop on Dope Analysis ; 13th to 18th February 2011 |
| Veröffentlicht: | Köln: Sportverl. Strauß (Verlag), 2011, S. 203-206, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Elektronische Ressource (Datenträger) |
| Sprache: | Englisch |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201211007387 |
| Quelle: | BISp |
Abstract
There are many kinds of microorganisms in environment. Some of them can degrade steroid structures. Such as Rhodococcus erythropolis can degrade testosterone to 4-androstene-3,17-dione and 1,4-androstadiene-3,17-dione. This kind of degradation may change steroids profile during routine screening procedure. The phosphate buffer (pH=6.9) is suitable for the microorganisms’ living. Some experiments were in conformation of this result. The microorganisms breed in the new prepared phosphate buffer are enough to degrade a large number of steroids, even if it was prepared by MILLIPORE purified water and stored at 4°C for 3 months. The aim of this study is to investigate how the microorganisms in this phosphate buffer degraded the endogenous steroids. Einleitung