Post-exercise cardiac troponin release is related to exercise training history
Deutscher übersetzter Titel: | Ausschüttung von kardialem Troponin ist mit dem sportlichen Training in der Vergangenheit verbunden |
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Autor: | Mehta, Ritan; Gaze, D.; Mohan, S.; Williams, K.L.; Sprung, V.; George, K.; Jeffries, R.; Hudson, Z.; Perry, M. ; Shave, R. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 33 (2012), 5, S. 333-337, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-0031-1301322 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201206004055 |
Quelle: | BISp |
Abstract
Marathon running can increase circulating cardiac troponin above the diagnostic criteria for myocardial infarction. We determined whether prior-exercise experience (training history) might be related to the magnitude of immediate post-race troponin release following completion of the London Marathon in a group of non-elite runners. Using a prospective study design, 52 runners were recruited into either HIGH T-E (trained-experience) (n=27) or LOW T-E (n=25) groups. Cardiac troponin I (cTnI) release following race completion was compared between these 2 groups. To examine relationships between cTnI release and participant demographic and indices of prior training experience an additional 52 runners who did not meet the criteria for either the HIGH T-E or LOW T-E groups were also recruited. The combined data from all 104 runners was analysed using multivariate linear regression analysis. The results revealed a significant difference in post marathon circulating cTnI between LOW T-E runners (median: 0.11 µg/L; interquartile range [IQR]: 0.03-0.18 µg/L) and HIGH T-E runners (median: 0.03 µg/L; IQR 0.02-0.057 µg/L) (p<0.05). Average miles run per week in the last 3 years, a marker of total training experience, encompassing training volume and duration, was negatively associated with post-marathon cTnI release (p<0.001). Verf.-Referat