Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats
Gespeichert in:
| Deutscher übersetzter Titel: | Einfluss moderater körperliche Aktivität auf die GH/IGF-1 Achse bei Ratten mit Diabetes |
|---|---|
| Autor: | Gomes, R.J.; Caetano, F.H.; Mello, M.A.R.; Luciano, E. |
| Erschienen in: | Biology of sport |
| Veröffentlicht: | 23 (2006), 3, S. 291-301, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 0860-021X, 2083-1862 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201101000809 |
| Quelle: | BISp |
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PU201101000809 |
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Literatur |
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2011-01-31T16:47:19Z |
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JOI200600030000250 |
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Biology of sport |
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Biology of sport, 2006, 3 |
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PU201101000809 |
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Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats |
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0291 |
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bisparticle |
| publishDate |
2006 |
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2006 |
| language |
eng |
| title |
Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats |
| spellingShingle |
Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats Aktivität, körperliche Blutuntersuchung Diabetes mellitus Hormonausschüttung Hormonhaushalt Schwimmen Sportmedizin Tierversuch Training, sportliches Untersuchung, vergleichende Wachstumshormon |
| title_sort |
influence of moderate physical training on the gh/igf1 axis in diabetic rats |
| title_short |
Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats |
| title_alt |
Einfluss moderater körperliche Aktivität auf die GH/IGF-1 Achse bei Ratten mit Diabetes |
| title_alt_lang |
deu |
| media_type |
Elektronische Ressource (online) Gedruckte Ressource |
| city |
Warschau |
| spelling |
Warszawa 0860-021X 2083-1862 639281-7 Aktivität, körperliche Blutuntersuchung Diabetes mellitus Hormonausschüttung Hormonhaushalt Schwimmen Sportmedizin Tierversuch Training, sportliches Untersuchung, vergleichende Wachstumshormon animal experiment blood test comparative study diabetes mellitus growth hormone hormone balance hormone release physical activity sports medicine sport training swimming Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Maus Ratte Tierexperiment Diabetes, mellitus Aktivität, motorische Bewegungsaktivität Aktivität Ausbildung, sportliche Bewegungstraining Schulung Sportarttraining Training Training, motorisches Training, sportartspezifisches Trainingsbetrieb Trainingspraxis Trainingsprozess Trainingssystem Trainingstechnologie Trainingszeit Trainingsziel Ausscheidung Hormonproduktion Vergleich Schwimmer Fahrtenschwimmen Freischwimmen Hechtschiessen Schwimmen, therapeutisches Schwimmerin Schwimmerschulter Schwimmtechnik Schwimmverein Blutanalyse training for sport comparative investigation somatotropic hormone somatotropin STH Influence of moderate physical training on the GH/IGF-1 axis in diabetic rats PU201101000809 201101000809 |
| abstract |
The influence of moderate physical training on serum growth hormone (GH), insulin-like growth factor –1 (IGF-1) and binding protein ( IGFBP-3) in experimental diabetic rats was investigated. Male Wistar rats were divided into 4 groups, sedentary control (SC), trained control (TC), sedentary diabetic (SD) and trained diabetic (TD). Experimental diabetes was induced of Alloxan (35mg/b.w.) The training program consisted by swimming 5 days/week, 1 h/day, supporting a load of 2.5 % b.w., during 6 weeks. Then, the rats were sacrificed and blood was collected for determinations of serum glucose, insulin, GH, IGF-1 and IGFBP-3. Samples of liver were used to evaluate glycogen, protein and DNA contents. The results were analyzed by ANOVA, and Bonferroni test and the significance level was set at 2.5 %. Diabetes decreased serum GH, IGF-1, IGFBP-3 and liver glycogen stores in SD group. Physical training promoted increase in serum IGF-1 in both TC and TD groups (SC=82 ± 15; TC=103 ± 13; SD=77 ± 16; TD=112 ± 29 ng/ml) and liver glycogen store in TD group when compared to SD (SC=5.2 ± 1.2; TC= 6.2 ± 1; SD=2 ± 0.5; TD=5 ± 1.8 mg/100mg). Therefore, physical training contributes to the increase in liver glycogen content and to rise of insulin-like growth factor level in diabetic rats. It was concluded that moderate physical training promotes important adaptations related to GH-IGF-1 axis in diabetic organisms. Verf.-Referat |
| abstract_lang |
eng |
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abstract |
| author2 |
Gomes, R.J. Caetano, F.H. Mello, M.A.R. Luciano, E. |
| author_facet |
Gomes, R.J. Caetano, F.H. Mello, M.A.R. Luciano, E. |
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Autor Autor Autor Autor |
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|
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Gomes, R.J. Caetano, F.H. Mello, M.A.R. Luciano, E. |
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0/Autor/ 1/Autor/Gomes, R.J./ 0/Autor/ 1/Autor/Caetano, F.H./ 0/Autor/ 1/Autor/Mello, M.A.R./ 0/Autor/ 1/Autor/Luciano, E./ |
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http://biolsport.com/fulltxt.php?ICID=890842 |
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fulltext |
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1 |
| issn |
0860-021X 2083-1862 |
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639281-7 |
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0/Polen/ |
| topic |
Aktivität, körperliche Blutuntersuchung Diabetes mellitus Hormonausschüttung Hormonhaushalt Schwimmen Sportmedizin Tierversuch Training, sportliches Untersuchung, vergleichende Wachstumshormon |
| topic_facet |
Aktivität, körperliche Blutuntersuchung Diabetes mellitus Hormonausschüttung Hormonhaushalt Schwimmen Sportmedizin Tierversuch Training, sportliches Untersuchung, vergleichende Wachstumshormon |
| topic_en |
animal experiment blood test comparative study diabetes mellitus growth hormone hormone balance hormone release physical activity sports medicine sport training swimming |
| topic_en_facet |
animal experiment blood test comparative study diabetes mellitus growth hormone hormone balance hormone release physical activity sports medicine sport training swimming |
| synonym |
Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Maus Ratte Tierexperiment Diabetes, mellitus Aktivität, motorische Bewegungsaktivität Aktivität Ausbildung, sportliche Bewegungstraining Schulung Sportarttraining Training Training, motorisches Training, sportartspezifisches Trainingsbetrieb Trainingspraxis Trainingsprozess Trainingssystem Trainingstechnologie Trainingszeit Trainingsziel Ausscheidung Hormonproduktion Vergleich Schwimmer Fahrtenschwimmen Freischwimmen Hechtschiessen Schwimmen, therapeutisches Schwimmerin Schwimmerschulter Schwimmtechnik Schwimmverein Blutanalyse |
| synonym_en |
training for sport comparative investigation somatotropic hormone somatotropin STH |
| journal_facet |
Biology of sport |
| container_title |
Biology of sport |
| container_volume |
23 |
| container_issue |
3 |
| container_start_page |
S. 291-301 |
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1 |
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BISp |
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JO00000000250 |
| journal_year |
2006 |
| journal_issue |
3 |
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1791512803618586624 |
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13,546046 |