Abstract

Human chorionic gonadotropin hormone (hCG) is included on WADA's Prohibited List, Section S2. Following some studies developed on large pools of athletes and some statistical reviews, a cut-off value of 5 mUI/mL has been recommended as doping threshold. hCG is a glycoprotein that may be used by athletes to stimulate testosterone production before competition and/or to prevent testicular atrophy during and after prolonged administration of anabolic androgens. This paper work shows the results obtained after intramuscular administration of hCG on three subjects and its influence on steroid profile. Conclusions: the maximum value of the urinary concentration of the ß-hCG after administration of Pregnyl was observed at 24 hours; hCG administration caused in all the volunteers the stimulation of the testosterone and epitestosterone endogenous secretion; VE ratio values are below the limit although the testosterone and epitestosterone values show significant increases in comparation with the values before administration; we consider that in order to confirm these results, more studies an a larger number of volunteer subjects are necessary. Aus dem Text (geändert)