DNA typing for the confirmation of manipulation in dope control: a casework
| Deutscher übersetzter Titel: | DNS-Typing zur Bestaetigung von Manipulation in der Dopingkontrolle: eine Falldarstellung |
|---|---|
| Autor: | Geyer, Hans; Berschick, P.; Marek-Engelke, U.; Schänzer, Wilhelm |
| Herausgeber: | Schänzer, Wilhelm; Geyer, Hans; Gotzmann, Andrea; Marek-Engelke, U. |
| Erschienen in: | Recent advances in doping analysis (5) : Proceedings of the Manfred Donike Workshop ; 15th Cologne Workshop on Dope Analysis ; 23rd to 28th February 1997 |
| Veröffentlicht: | Köln: Sport u. Buch Strauß (Verlag), 1998, 1998. S. 301, Lit., Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Gedruckte Ressource |
| Sprache: | Englisch |
| ISBN: | 3890010164 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199805301879 |
| Quelle: | BISp |
Abstract des Autors
In routine dope control a manipulation - six different athletes delivered identical urines - could be detected by the screening method for volatile nitrogen containing substances, by steroid profiling and by HPLC finger printing. The results were confirmed by PCR based analysis of urinary DNA with the two STR (short tandem repeat polymorphism) systems FGA (HUMFIBRA) and D18S51. According to our knowledge, this is the first documented case in dope control, where DNA typing was used to prove manipulation of urine samples. The advantage of the DNA typing is the possibility to individualize the urine samples by comparison of urine and blood results. In table 1 are presented steroid profiling data and data of DNA typing with the two STR Systems. Verf.-Referat