The process of bone response to running training in female growing rats

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Deutscher übersetzter Titel:Prozesse im wachsenden Knochen als Reaktion auf Lauftraining bei weiblichen Ratten
Autor:Fukuda, R.; Usuki, S.; Mukai, N.; Amagai, H.; Kotani, E.; Hayashi, K.; Takamatsu, K.
Erschienen in:Japanese journal of physical fitness and sports medicine
Veröffentlicht:46 (1997), 5, S. 513-521, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Japanisch
ISSN:0039-906X, 1881-4751
Schlagworte:
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Erfassungsnummer:PU199805301798
Quelle:BISp
id PU199805301798
bisp-collection db
format Literatur
last_indexed 2009-04-27T15:32:47Z
first_indexed 2001-07-24T13:40:52Z
publication_source BISp
subformat Zeitschriftenartikel
hierarchy_top_id JO00000000690
hierarchy_parent_id JOI199700050000690
hierarchy_top_title Japanese journal of physical fitness and sports medicine
hierarchy_parent_title Japanese journal of physical fitness and sports medicine, 1997, 5
is_hierarchy_id PU199805301798
is_hierarchy_title The process of bone response to running training in female growing rats
hierarchy_sequence 0513
recordtype bisparticle
publishDate 1997
publishDate_facet 1997
language jpn
title The process of bone response to running training in female growing rats
spellingShingle The process of bone response to running training in female growing rats
Belastung, mechanische
Frau
Knochen
Knochendichte
Lauftraining
Osteocalcin
Osteogenese
Reifung
Sportmedizin
Tierversuch
Wachstumsalter
Wachstumsfaktor
Östrogen
title_sort the process of bone response to running training in female growing rats
title_short The process of bone response to running training in female growing rats
title_alt Prozesse im wachsenden Knochen als Reaktion auf Lauftraining bei weiblichen Ratten
title_alt_lang deu
media_type Gedruckte Ressource
city Tokio
abstract Physical activity in the growing period has been shown to be effective for increasing bone mass because immature bones are more sensitive than mature adult bones to the stimulation with mechanical stress. However, bone growth is not uniform and changes markedly at puberty. Therefore, the response of bone to exercise may differ according to the growth process. The purpose of the present study was to investigate the process of the bone response to running training, and the relationship between the bone response and serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3) levels in female rats. Thirty-three female Wistar-Imamichi rats 4 weeks of age were divided randomly into control (CON) and running training (RUN) groups for 6 and 12 weeks. Training consisted of running on a flat-bed treadmill at 30 m/min for 60 min/day, 5 days/week. The bone mineral content (BMC) and bone mineral density (BMD) in the whole and five parts of the tibia were measured by a dual-energy X-ray absorptiometer (DXA). Simultaneously, we measured serum concentrations of IGF-I, IGFBP-3, osteocalcin and 17 beta-estradiol. The whole tibial BMD was analyzed at five different studied parts within the same tibia, the increase of BMD was noted in the proximal and distal cancellous bone in the 6-week RUN group, and in the diaphysal, cortical bone in the 12-week RUN group. Serum concentrations of osteocalcin, a marker of bone formation, were not altered by training, whereas they decreased with aging. Serum IGF-I levels in the training groups were not changed, but IGFBP-3 levels were increased significantly only in 6-week RUN rats. As a complex between IGFBP-3 and IGF-I may be more improving than free IGF-I in the bone formation, the high levels of IGFBP-3 in the 6-week RUN group may induce an increase in the activity of IGF-I. There was a significant positive relationship between serum IGF-I concentration and BMD of the whole tibia in the 6-week study and between the IGFBP-3 level and BMD in both the 6 and 12-week studies. In conclusion, 1) the process of the skeletal response to running training is site-specific within the same bone, and 2) the increment of the IGFBP-3 level with training in the growth period may reflect the increment of tibial BMD through training. Verf.-Referat
abstract_lang eng
abstract_type author
author2 Fukuda, R.
Usuki, S.
Mukai, N.
Amagai, H.
Kotani, E.
Hayashi, K.
Takamatsu, K.
author_facet Fukuda, R.
Usuki, S.
Mukai, N.
Amagai, H.
Kotani, E.
Hayashi, K.
Takamatsu, K.
author2-role Autor
Autor
Autor
Autor
Autor
Autor
Autor
author2-authorityid






author_author_facet Fukuda, R.
Usuki, S.
Mukai, N.
Amagai, H.
Kotani, E.
Hayashi, K.
Takamatsu, K.
author2-synonym






author2_hierarchy_facet 0/Autor/
1/Autor/Fukuda, R./
0/Autor/
1/Autor/Usuki, S./
0/Autor/
1/Autor/Mukai, N./
0/Autor/
1/Autor/Amagai, H./
0/Autor/
1/Autor/Kotani, E./
0/Autor/
1/Autor/Hayashi, K./
0/Autor/
1/Autor/Takamatsu, K./
issn 0039-906X
1881-4751
spelling 0039-906X
1881-4751
TAKAA
600775-2
Belastung, mechanische
Frau
Knochen
Knochendichte
Lauftraining
Osteocalcin
Osteogenese
Reifung
Sportmedizin
Tierversuch
Wachstumsalter
Wachstumsfaktor
Östrogen
animal experiment
bone
bone density
estrogen
growth age
growth factor
maturation
mechanic load
osteocalcin
osteogenesis
running training
sports medicine
woman
Adoleszenz
Knochenzyste
Spongiosaplastik
Knochenspan
Knochenradiographie
Osteoplastik
Belastung
Laufschulung
Knochenkern

Diskriminierung, geschlechtliche
Frauengymnastik
Frauentraining
Hausfrau
Maturität
Pubeszenz
Reife
Maus
Ratte
Tierexperiment
Medizin
Geschichte der Medizin
Untersuchung, sportmedizinische
Wasserdampf
run training
The process of bone response to running training in female growing rats
PU199805301798
199805301798
coden TAKAA
zdb 600775-2
location_hierarchy_facet 0/Japan/
topic Belastung, mechanische
Frau
Knochen
Knochendichte
Lauftraining
Osteocalcin
Osteogenese
Reifung
Sportmedizin
Tierversuch
Wachstumsalter
Wachstumsfaktor
Östrogen
topic_facet Belastung, mechanische
Frau
Knochen
Knochendichte
Lauftraining
Osteocalcin
Osteogenese
Reifung
Sportmedizin
Tierversuch
Wachstumsalter
Wachstumsfaktor
Östrogen
topic_en animal experiment
bone
bone density
estrogen
growth age
growth factor
maturation
mechanic load
osteocalcin
osteogenesis
running training
sports medicine
woman
topic_en_facet animal experiment
bone
bone density
estrogen
growth age
growth factor
maturation
mechanic load
osteocalcin
osteogenesis
running training
sports medicine
woman
synonym Adoleszenz
Knochenzyste
Spongiosaplastik
Knochenspan
Knochenradiographie
Osteoplastik
Belastung
Laufschulung
Knochenkern

Diskriminierung, geschlechtliche
Frauengymnastik
Frauentraining
Hausfrau
Maturität
Pubeszenz
Reife
Maus
Ratte
Tierexperiment
Medizin
Geschichte der Medizin
Untersuchung, sportmedizinische
Wasserdampf
synonym_en run training
journal_facet Japanese journal of physical fitness and sports medicine
container_title Japanese journal of physical fitness and sports medicine
container_volume 46
container_issue 5
container_start_page S. 513-521
has_references 1
institution BISp
journal_fac JO00000000690
journal_year 1997
journal_issue 5
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score 13,538135