The asthmatic athlete: metabolic and ventilatory responses to exercise with and without pre-exercise medication

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Bibliographic Details
Title translated into German:Der asthmakranke Sportler: Stoffwechsel- und Atmungsreaktionen auf koerperliche Belastung mit und ohne vorherige Medikation
Author:Ienna, T.M.; McKenzie, D.C.
Published in:International journal of sports medicine
Published:18 (1997), 2 , S. 142-148, Lit.
Format: Publications (Database SPOLIT)
Publication Type: Journal article
Media type: Print resource Electronic resource (online)
ISSN:0172-4622, 1439-3964
Online Access:
Identification number:PU199703203202

Author's abstract

To determine whether asthmatic athletes have normal physiological responses to exercise without pre-exercise medication, we studied 17 female and male asthmatic subjects, 9 highly trained (HT) and 8 moderately trained (MT) under 2 conditions: salbutamol (S) 200 micro-g taken via inhaler 15 minutes prior to exercise or placebo (PL). The exercise task was 4 continuous 5 minute increments representing 25, 50, 75 and 90% of the subject's VO2max. VO2, minute ventilation (VE), respiratory exchange ratio (RER), % saturation (SaO2), and HR were continuously measured during exercise. Blood lactate (LA) was measured each minute throughout exercise and recovery. Post-medication, exercise, and recovery measurements of peak expiratory flow rates (PEFR) were made using a Mini-Wright flow meter. No differences (p>0.05) between treatment conditions were found at any stage of exercise with respect to VO2, VE, RER, HR and SaO2. However, among the HT group the mean HR for the 4 exercise conditions was significantly higher under PL (PL=151.7; S=147.2; p=0.01). No difference was found in LA during exercise or in recovery. Pre-exercise PEFR was significantly higher when pretreatment was S (S=582; PL=545 l/sec; p=0.003). During the exercise and recovery conditions mean PEFR measures were significantly higher (S=600.1; PL=569.6; p=0.002) with the S treatment. Bonferroni's test detected a difference in PEFR measures between S and PL at 25% and 50% VO2max and 3 and 15 minutes into recovery. There was no difference in the physiological response to exercise between groups based on training status. It was concluded that although S affects the PEFR, these asthmatic athletes do not have altered metabolic or ventilatory responses during this incremental exercise protocol. Verf.Referat