Urinausscheidung von Methylhistamin nach maximaler Fahrradergometrie

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Bibliographische Detailangaben
Englischer übersetzter Titel:Excretion of methylhistamine after a maximal exercise test
Autor:Heine, O.; Prinz, U.; Soll, C.; Rost, R.; Dufaux, Bertin
Herausgeber:Liesen, Heinz; Baum, Matthias; Weiß, Michael
Erschienen in:Regulations- und Repairmechanismen : 33. Deutscher Sportärztekongress Paderborn 1993
Veröffentlicht:Köln: Dt. Ärzte-Verl. (Verlag), 1994, 1994. S. 373-375, Abb., Lit., Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Sammelwerksbeitrag
Medienart: Gedruckte Ressource
Sprache:Deutsch
ISBN:3769103084
Schlagworte:
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Erfassungsnummer:PU199503075653
Quelle:BISp

Abstract des Autors

Few reports on the effect of physical exercise on histamine have been published. An increase of histamine in plasma during exercise has been described, and in a recent study no effect of an antihistamine ingestion on exercise performance or maximal oxygen uptake could be demonstrated. Attempting to clarify the physiological significance of histamine during exercise, we measured methylhistamine, which is a major catabolic of histamine, in urine before and after a standardised maximal bicycle exercise test. 10 students of physical education participated in the study. Methylhistamine was measured in urine by radioimmuno-assay before and after exercise. To compensate the differences of urine volume before and after exercise the methylhistamine values were expressed as micro-g per g creatinine. The amount of methylhistamine excreted before exercise was 173 +/- 85 mircro-g/g creatinine and after exercise 153 +/- 48 micro-g/g creatinine. The difference was not significant. The results question earlier studies about a liberation of histamine in blood during exercise. The changes in concentration of histamine during exercise might be the result of an altered catabolism and not the consequence of an active secretion by basophile granulocytes. Verf.-Referat