Abstract des Autors

The effects of prolonged restriction of feed intake with simultaneous systematic physical exercise on the utilization of carbohydrates were studied in rats. The animals were fed for 4 weeks standard diet ad libitum (Group I), the same diet with the intake reduced to 50% of that of the control group (Group II), or the same diet and the level of intake, but given ad libitum 24 h prior to the last exercise (Group III). The animals performed treadmill exercises every other day. Marked decreases in body mass and liver glycogen, somewhat smaller decrease in the glycogen content in the soleus muscle, decrease in serum triglycerides, and a very high increase in serum glycerol, were observed in Group II vs. the control group. Refeeding ad libitum the animals from Group III after 4 weeks of restricted feed intake led, within 24 h, to hypercompensatory regeneration of glycogen stores, and to normalization of triglyceride and glycerol levels in serum both at rest and following exercise. Feed intake restriction did not affect pre- or post-exercise blood glucose levels. The results suggest that feeding low-calorie diet induces adaptive adjustment of energy demand in exercise, leaving the carbohydrate stores only slightly diminished. A short-lasting refeeding ad libitum normalizes the metabolic responses to exercise. Verf.-Referat