TY - JOUR AU - Meeuwisse, Willem H. A2 - Meeuwisse, Willem H. A2 - McKenzie, Donald C. A2 - Hopkins, Susan R. A2 - Road, Jeremy D. DB - BISp DP - BISp KW - Bronchospasmolytikum KW - Dopingkontrolle KW - Herzfrequenz, maximale KW - Leistungsbeeinflussung KW - Leistungssportler KW - Lungenfunktion KW - Pharmakologie KW - Pharmakon KW - Sauerstoffaufnahme, maximale KW - Sekundenkapazität KW - Sportmedizin KW - Sprint LA - eng TI - The effect of salbutamol on performance in elite nonasthmatic athletes TT - Der Einfluss von Salbutamol auf die Leistung von nicht-asthmatischen Spitzensportlern PY - 1992 N2 - The effect of salbutamol on performance was studied in seven male nonasthmatic highly trained (VO2max >/= 60 ml/kg/min) cyclists. Salbutamol (S = 2 puffs = 200 micro-g) or placebo (P) was administered by metered-dose inhaler, through a spacer device, 20 min prior to testing in a double-blind, randomized cross-over design. Testing sessions on a cycle ergometer included the measurement of maximal oxygen uptake (VO2max), peak power, maximal heart rate, and pulmonary function. A timed sprint to exhaustion was performed after 45 min of exercise at 70 of VO2max, and a Wingate anaerobic test was used to measure total work and peak power. There was a nonsignificant decrease in VO2max (P = 63.5 +/- 3.2; S = 62.6 +/- 3.3 ml/kg/min). No difference was found in peak power, maximum heart rate, endurance sprint time, Wingate peak power, or total work. After an anticipated baseline increase was taken into account, the pattern of change in FEV1 over time did not differ between salbutamol and placebo. It was concluded that a therapeutic dose of aerosol salbutamol does not have an ergogenic effect in elite nonasthmatic athletes, and it is therefore recommended that inhaled salbutamol continue to be permitted in international competition for individuals with exercise induced bronchospasm. Verf.-Referat SP - S. 1161-1166 SN - 0195-9131 JO - Medicine and science in sports and exercise IS - 10 VL - 24 M3 - Gedruckte Ressource ID - PU199304062073 ER -