Magnetic resonance spectroscopy and imaging of muscle - a physiological approach
Deutscher übersetzter Titel: | Magnetresonanzspektroskopie und -darstellung - aus physiologischer Sicht |
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Autor: | Edwards, R.H.T.; Gibson, H.; Roberts, N.; Clague, J.E.; Martin, P.A. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 13 (1992), Suppl.1, S. S143-146, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199304061972 |
Quelle: | BISp |
Abstract
Magnetic resonance spectroscopy (MRS) and imaging (MRI) are now well established techniques for the study of cellular metabolism and gross structure of muscle. Using non-ferrous materials, we have constructed a system for the measurement of isometric force of quadriceps in response to percutaneous electrical stimulation and voluntary effort within the bore of a 48 cm diameter 1.5 T General Electric SIGNA whole body MR system. Using this system we have been able to study the relationship between electromechanical coupling and chemistry of muscle, with 31-P MRS for the mesurement of high-energy phosphates and pH, during electrically stimulated activity. Image analysis using the Context Vision system enables a distinction to be made, in 1-H MRI by T1/T2 mapping, of muscle, fat and connective tissue to give force per unit cross sectional area of muscle. The combination of MR and functional measurements provide a valuable tool for further detailed analysis of human muscle weakness and fatigue. Verf.-Referat