TY  - JOUR
AU  - Secher, N.H.
A2  - Secher, N.H.
A2  - Kjær, Michael
A2  - Galbo, H.
DB  - BISp
DP  - BISp
KW  - Blutdruckregulation
KW  - Gefäßwiderstand
KW  - Herz-Kreislauf-System
KW  - Herzfrequenzregulation
KW  - Innervation
KW  - Kreislaufanpassung
KW  - Muskelarbeit, dynamische
KW  - Nervenreaktion
KW  - Ruhe-Belastungs-Übergang
KW  - Sportmedizin
KW  - Vasodilatation
LA  - eng
TI  - Arterial blood pressure at the onset of dynamic exercise in partially curarized man
TT  - Arterieller Blutdruck am Beginn dynamischer Muskelarbeit bei zum Teil kurarisierten Menschen
PY  - 1988
N2  - In six young men, heart rate and arterial mean blood pressure responses to the onset of light dynamic exercise 99 W (range 59-138) on a stationary bicycle were followed during partial neuromuscular blockade with tubocurarine. Tubocurarine was used in order to accentuate the central nervous (central command) influence on the cardiovascular variables and reduced hand-grip strength to 42 (36-47) of control. At the onset of exercise heart rate increased immediately and similarly with and without neuromuscular blockade. Mean arterial blood pressure remained constant during the first 6 s of control exercise and then increased. With tubocurarine a decrease of 9 mmHg (3-12) was seen during the first 6 s before blood pressure increased. The similar heart rate responses seen with and without neuromuscular blockade indicate that central command has little influence on this variable at the onset of dynamic exercise. The constant blood pressure at the onset of control exercise suggests that the immediate changes in cardiac output and peripheral vascular resistance, respectively, are accurately matched. The decrease in blood pressure at the onset of exercise with tubocurarine suggests that central command stimulates vasodilatating nerves to arterioles in the working muscles. Verf.-Referat
SP  - S. 233-237
SN  - 0001-6772
JO  - Acta physiologica Scandinavica
IS  - 2
VL  - 133
M3  - Gedruckte Ressource
ID  - PU198806034565
ER  -