In vivo 31P-NMR in human muscle: transient patterns with exercise

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Bibliographic Details
Title translated into German:In vivo 31P-NMR im menschlichen Muskel: Uebergangsmuster zu Beginn der Muskelarbeit
Author:Mole, P.A.; Coulson, R.L.; Caton, J.R.; Nichols, B.G.; Barstow, T.J.
Published in:Journal of applied physiology
Published:59 (1985), 1 , S. 101-104, Lit.
Format: Publications (Database SPOLIT)
Publication Type: Journal article
Media type: Print resource
Language:English
ISSN:8750-7587
Keywords:
ATP
Online Access:
Identification number:PU198702027944
Source:BISp

Abstract

Evaluation of dynamic changes in pH and concentrations of adenosine 5-triphosphate (ATP), phosphocreatine (PCr), and inorganic phosphate (Pi) during the transition from rest to steady-state exercise in the human has been methodologically limited. Previous work has relied on muscle biopsy of exercising subjects at different times in different exercise bouts. Chemical evaluation of metabolites has been hampered by continuing change in metabolic concentration during the biopsy procedure. Recently, Fourier-transformed 31P nuclear magnetic resonance (31P-NMR), employing surface coils, has made evaluation of phosphorus metabolites possible by noninvasive atraumatic means in human muscle. Relative concentrations of PCr, Pi, and ATP, together with pH, have been obtained with 31P-NMR from the flexor digitorum superficialis muscle on two occasions in four adult men during the transition from rest to exercise. (PCr) rapidly fell and was mirrored by a rise in (Pi). The former temporarily exceeded the latter with the discrepancy apparently being absorbed by a transient rise in (ATP), which was itself mirrored by alteration in (H+). Verf.-Referat