Abstract

Five sedentary male volunteers were studied to observe the effects of short-term physical training on glycolysis in venous erythrocytes. The training protocol consisted of a 30-min ride on a bicycle ergometer with a load of 200 W on 6 days/week for 2 weeks. The subjects were exercised under the same conditions before and after the training program. Cardiopulmonal capacity appeared to be essentially unaffected by the training. In the control values after training, however, there were a significant decrease in hematocrit and a downward trend in hemoglobin, suggesting a slight tendency to anemia. When the concentrations of 12 glycolytic intermediates after training were presented in form of a crossover plot, there were significant decreases in glucose-6-phosphate, furctose-6-phosphate, pyruvate and lactate concentrations immediately after exercise and a negative crossover point seemed to exist between phosphoenolpyruvate and pyruvate. On the other hand, there were no significant changes in the intermediates to controls or after 30-min rest after training. The results suggested that erythrocytes during exercise at similar absolute work loads after training demand less fuel substrate, glucose, than before training and that determination of glycolysis in human erythrocytes may provide an index of physical training. Verf.-Referat