Abstract

Physical exercise has profound effects upon total plasma triglycerides (TG) as well as on the activity of the enzyme lipoproteinlipase (LPL). We studied the effect of the 24 h endurance race of Pinzolo, Italy, on plasma lipids lipoproteins and apoproteins in male cross-country skiers, who run from 95 to 260 km. Cholesterol (Chol) and TG were determined enzimatically, lipoprotein-Chol was determined after serum fractionation by sequential ultracentrifugation. Apo B and A I were determined using monospecific antisera raised in rabbits by radioimmunodiffusion. After the 24 h race plasma TG decreased significantly; plasma-Chol however remained constant. The Chol distribution among plasma lipoproteins was dramatically modified: VLDL-Chol and LDL-Chol dropped significantly; HDL-Chol increased. Apo B significantly decreased, while apo A I remained constant. From these data we conclude that a 24 h endurance race reduces TG and lipoproteins to lower levels than those found in subjects undergoing aerobic exercise for shorter time. All those changes are consistent with an increased activity of the LPL. Verf.-Referat