Effects of endurance training on myocardial myosin adenosine triphosphatase activity of the dog

Gespeichert in:
Bibliographische Detailangaben
Deutscher übersetzter Titel:Wirkung von Ausdauertraining auf die Myosin-Adenosintriphosphatase-Aktivitaet im Herzmuskel des Hundes
Autor:Carey, Rita A.; Ritzer, Theodore F.; Bove, Alfred A.
Erschienen in:Medicine and science in sports and exercise
Veröffentlicht:11 (1979), 3, S. 308-312, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Englisch
ISSN:0195-9131, 1530-0315
Schlagworte:
Online Zugang:
Erfassungsnummer:PU198006012248
Quelle:BISp

Abstract

Endurance exercise training has been found to enhance the functional capacity of the myocardium in several animal models. The sub-cellular phenomena accompanying the augmented function are yet to be explained. The present study sought to determine if the myosin ATPase activity of cardiac muscle increased as a result of endurance conditioning. Five beagles trained by running on a motor driven treadmill (T) and five control (NT) animals were studied. Following 10 weeks of training the T group had a significantly lower heart rate than the NT while performing the same submaximal exercise and the gastrocnemius cytochrome oxidase activity was significantly greater in the T than in the NT. These two measurements established that the exercised animals were physically trained. Myosin was isolated from the left ventricular myocardium and activated in a medium containing K-EDTA. No significant difference inmaximum myosin ATPase activity was observed between the NT and T groups in cardiac muscle. It was concluded that cardiac muscle myosin ATPase activity was not affected by 10 weeks of endurance conditioning induced by treadmill running in dogs. Verf.-Referat