Interrelationships between changes in erythropoietin, plasma volume, haemoglobin concentration, and total haemoglobin mass in endurance athletes

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Deutscher übersetzter Titel:Zusammenhänge zwischen Veränderungen des Erythropoetins, des Plasmavolumens, der Hämoglobinkonzentration und der gesamten Hämoglobinmasse bei Ausdauersportlern
Autor:Sitkowski, Dariusz; Szygula, Zbigniew; Pokrywka, Andrzej; Turowski, Dariusz; Malczewska-Lenczowska, Jadwiga
Erschienen in:Research in sports medicine
Veröffentlicht:26 (2018), 3, S. 381-389, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:1543-8627, 1543-8635
DOI:10.1080/15438627.2018.1447936
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Erfassungsnummer:PU201901000227
Quelle:BISp

Abstract des Autors

Interrelationships between physiological changes (Δ) in erythropoietin (EPO), plasma volume (PV), haemoglobin concentration ([Hb]), and total haemoglobin mass (tHb-mass) were examined in cyclists who trained in different altitudes. Regardless of differences in pattern of changes observed in three training locations, ΔEPO was correlated positively with ΔPV, negatively with Δ[Hb], and trivially with ΔtHb-mass. Δ[Hb] was negatively correlated with ΔPV. In the pooled data the Spearman’s rank correlation coefficients were as follows: r = 0.783, P < 0.001; r = −0.704, P < 0.001; r = 0.136, P > 0.05; r = −0.813, P < 0.001, respectively. The obtained results have shown that EPO does not only regulate [Hb] by erythropoiesis stimulation but also by PV modulation, which probably aims at keeping proper level of arterial oxygen content for oxygen delivery to tissues.