Resting extracellular signal-regulated protein kinase 1/2 expression following a continuum of chronic resistance exercise training paradigms
Deutscher übersetzter Titel: | Die Expression der extrazellulären signalregulierten Proteinkinase 1/2 in Ruhe nach einem Kontinuum von chronischen Krafttrainingsparadigmen |
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Autor: | Galpin, Andrew J.; Fry, Andrew C.; Nicoll, Justin X.; Moore, Christopher A.; Schilling, Brian K.; Thomason, Donald B. |
Erschienen in: | Research in sports medicine |
Veröffentlicht: | 24 (2016), 3, S. 298-303, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 1543-8627, 1543-8635 |
DOI: | 10.1080/15438627.2016.1202825 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201803001790 |
Quelle: | BISp |
Abstract des Autors
Extracellular signal-regulated protein kinase 1/2 (ERK1/2) moderates skeletal muscle growth; however, chronic responses of this protein to unique resistance exercise (RE) paradigms are yet to be explored. The purpose of this investigation was to describe the long-term response of ERK1/2 following circuit weight training (CWT), recreationally weight training (WT), powerlifting (PL) and weightlifting (WL). Independent t-tests were used to determine differences in trained groups compared to sedentary controls. Total ERK1/2 content was lower in PL and WL compared to their controls (p ≤ 0.05). Specific trained groups displayed large (WL: pERK/total-ERK; d = 1.25) and moderate (CWT: total ERK1/2; d = 0.54) effect sizes for altered kinase expression compared to controls. The results indicate ERK1/2 expression is down-regulated after chronic RE in well-trained weightlifters and powerlifters. Lower expression of this protein may be a method in which anabolism is tightly regulated after many years of high-intensity RE.