Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise
Deutscher übersetzter Titel: | Polyamine, schwere Ketten des Myosins und kollagen-spezifische Aminosäuren nach einer folgenden Einheit von exzentrischer Belastung |
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Autor: | Behringer, Michael; Montag, Johannes Caspar Konrad; Kilian, Yvonne; Heaton, Phil; Mester, Joachim |
Erschienen in: | Research in sports medicine |
Veröffentlicht: | 24 (2016), 3, S. 272-282, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 1543-8627, 1543-8635 |
DOI: | 10.1080/15438627.2016.1202830 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201803001788 |
Quelle: | BISp |
Abstract des Autors
We investigated alternatives to commonly used biomarkers of exercise-induced tissue damage. Over 5 days following two bouts of 100 drop-to-vertical jumps (inter-bout rest period of 3 weeks), myosin heavy chain 1, hydroxylysine (HYL), hydroxyproline (HYP), spermine (SPM) and spermine synthase (SMS) were measured in the serum of 10 participants. HYL significantly increased from 5.92 ± 1.49 ng/mL to 6.48 ± 1.47 ng/mL at 24 h. A similar trend was observed for bout 2, but without reaching significance. SPM significantly increased only after bout 1 from 0.96 ± 0.19 ng/mL at pretest to a peak level of 1.12 ± 0.26 ng/mL at 24 h, while B2 increments remained non-significant. Myosin heavy chain 1, HYP and SMS values remained below the detection limit of the applied enzyme-linked immunosorbent assay (ELISA) kit. Though HYL and SM increased after the intervention, both markers showed a large standard deviation (SD) combined with small increments. Therefore, none of the investigated biomarkers provides a meaningful alternative to commonly used damage markers.