Validity and reliability of a novel salivary immunoassay for individual profiling in applied sports science
Deutscher übersetzter Titel: | Validität und Reliabilität eines neuen Immunoassays mittels Speichel zur individuellen Profilerstellung in der angewandten Sportwissenschaft |
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Autor: | Coad, Sam; McLellan, Christopher P.; Whitehouse, Timothy; Gray, Bon |
Erschienen in: | Research in sports medicine |
Veröffentlicht: | 23 (2015), 2, S. 140-150, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 1543-8627, 1543-8635 |
DOI: | 10.1080/15438627.2015.1005300 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201510007754 |
Quelle: | BISp |
Abstract des Autors
The aim of this study was to examine the validity and reliability of a novel immunoassay, developed to assess salivary Immunoglobulin A (s-IgA). Validity and reliability of the Individual Profiling Lateral Flow Device (IPRO LFD) for s-IgA concentrations ([s-IgA]) was assessed in males (n = 12) and females (n =13) who were involved in recreational activities. Reliability of the IPRO LFD method was assessed by comparing [s-IgA] of two saliva samples collected concurrently, while validity was assessed by comparing with an enzyme-linked immunosorbent assay (ELISA) method. The IPRO LFD had a strong positive correlation (r = 0.93, p < 0.001), with no difference in [s-IgA] compared with the ELISA. The IPRO LFD was considered reliable (ICC r = 0.89, p < 0.001 and CV = 9.40 percent) for measures of [s-IgA]. We concluded that the IPRO LFD method may be a substitute to the ELISA method for measurements of [s-IgA]. Verf.-Referat