A comparison of genetic variants between proficient low- and high-risk sport participants
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| Deutscher übersetzter Titel: | Ein Vergleich der genetischen Varianten zwischen geübten Sportlern in Niedrig- und Hochrisikosportarten |
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| Autor: | Thomson, Cynthia J.; Power, Rebecca J.; Carlson, Scott R.; Rupert, Jim L.; Michel, Grégory |
| Erschienen in: | Journal of sports sciences |
| Veröffentlicht: | 33 (2015), 18, S. 1861-1870, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 0264-0414, 1466-447X |
| DOI: | 10.1080/02640414.2015.1020841 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201509006804 |
| Quelle: | BISp |
Abstract
Athletes participating in high-risk sports consistently report higher scores on sensation-seeking measures than do low-risk athletes or non-athletic controls. To determine whether genetic variants commonly associated with sensation seeking were over-represented in such athletes, proficient practitioners of high-risk (n = 141) and low-risk sports (n = 132) were compared for scores on sensation seeking and then genotyped at 33 polymorphic loci in 14 candidate genes. As expected, athletes participating in high-risk sports score higher on sensation seeking than did low-risk sport athletes (P < .01). Genotypes were associated with high-risk sport participation for two genes (stathmin, (P = .004) and brain-derived neurotrophic factor (P = .03)) as well as when demographically matched subsets of the sport cohorts were compared (P < .05); however, in all cases, associations did not survive correction for multiple testing. Verf.-Referat