Effect of antioxidants and exercise on bone metabolism
Deutscher übersetzter Titel: | Wirkung von Antioxydantien und Training auf den Knochenstoffwechsel |
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Autor: | Maïmoun, L.; Simar, D.; Caillaud, C.; Peruchon, E.; Sultan, Charles; Rossi, Michel; Mariano-Goulart, D. |
Erschienen in: | Journal of sports sciences |
Veröffentlicht: | 26 (2008), 3, S. 251-258, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0264-0414, 1466-447X |
DOI: | 10.1080/02640410701501689 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201407006848 |
Quelle: | BISp |
Abstract
We examined the effects of antioxidant supplementation in association with progressive aerobic training on the bone metabolism of healthy elderly individuals. For 8 weeks, 13 participants (mean age 74 years) received vitamin C (500 mg) and vitamin E (100 mg) daily and participated in a supervised progressive aerobic training programme. After the 8 weeks, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations were increased significantly by 42.8% (P < 0.001) and 26.8% (P < 0.01) respectively, while parathyroid hormone concentration was decreased by 17.5% (p < 0.05). Of the bone markers, only bone alkaline phosphatase decreased, by 14.6% (P < 0.05). No variation was observed for ionized calcium, insulin-like growth factor-1 or insulin-like growth factor binding protein-3. Our findings suggest that 8 weeks of combined antioxidant supplementation and aerobic training modified vitamin D metabolism and parathyroid hormone concentration. These adaptations might counterbalance the unfavourable hormonal profile frequently observed in the elderly that predisposes them to accentuated age-related bone loss. Verf.-Referat