Urine dipstick analysis for identification of runners susceptible to acute kidney injury following an ultramarathon
Deutscher übersetzter Titel: | Urinstäbchen-Tests zur Messung des Risikos einer akuten Nierenschädigung bei Läufern nach einem Ultramarathon |
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Autor: | Hoffman, Martin D.; Stuempfle, Kristin J.; Fogard, Kevin; Hew-Butler, Tamara; Winger, James; Weiss, Robert H. |
Erschienen in: | Journal of sports sciences |
Veröffentlicht: | 31 (2013), 1, S. 20-31, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0264-0414, 1466-447X |
DOI: | 10.1080/02640414.2012.720705 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201309006389 |
Quelle: | BISp |
Abstract
This study examined whether urine dipstick testing might be useful to predict the development of acute kidney injury after an ultramarathon. Participants in the 2011 161-km Western States Endurance Run underwent post-race blood and urine dipstick analyses. Of the 310 race finishers, post-race urine dipstick testing was completed on 152 (49%) and post-race blood also was obtained from 150 of those runners. Based on “injury” and “risk” criteria for acute kidney injury of blood creatinine 2.0 and 1.5 times estimated baseline, respectively, 4% met the criteria for injury and an additional 29–30% met the criteria for risk of injury. Those meeting the injury criteria had higher creatine kinase concentrations (P < 0.001) than those not meeting the criteria. Urine dipstick tests that read positive for at least 1+ protein, 3+ blood, and specific gravity ≥ 1.025 predicted those meeting the injury criteria with sensitivity of 1.00 (95% confidence interval [CI] 0.54–1.00), specificity of 0.76 (95% CI 0.69–0.83), positive predictive value of 0.15 (95% CI 0.06–0.30), negative predictive value of 1.00 (95% CI 0.97–1.00), and likelihood ratio for a positive test of 4.2. We conclude that urine dipstick testing was successfully able to identify those individuals meeting injury criteria for acute kidney injury with excellent sensitivity and specificity. (Verf.-Ref.)