Acute toxicity and withdrawal syndromes related to gamma-hydroxybutyrate (GHB) and its analogues gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD)

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Deutscher übersetzter Titel:Akute Toxizität und Entzugssyndrome im Zusammenhang mit Gamma-Hydroxybutyrat (GHB) und seiner Analoga Gamma-Butyrolacton (GBL) und 1,4-Butanediol (1,4-BD)
Autor:Wood, David M.; Brailsford, Alan D.; Dargan, Paul I.
Erschienen in:Drug testing and analysis
Veröffentlicht:3 (2011), 7/8 (New psychoactive substances), S. 417-425, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:1942-7603, 1942-7611
DOI:10.1002/dta.292
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Erfassungsnummer:PU201111009753
Quelle:BISp

Abstract

Gamma-hydroxybutyrate (GHB) has been used as a recreational drug since the 1990s and over the last few years there has been increasing use of its analogues gamma-butyrolactone (GBL) and to a lesser extent 1,4-butanediol (1,4BD). This review will summarize the literature on the pharmacology of these compounds; the patterns and management of acute toxicity associated with their use; and the clinical patterns of presentation and management of chronic dependency associated with GHB and its analogues. Verf.-Referat