ACE DD genotype is unfavorable to Korean short-term muscle power athletes
Deutscher übersetzter Titel: | Der ACE-DD-Genotyp wirkt sich ungünstig für koreanische Sprint-Sportler aus |
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Autor: | Kim, C.-H.; Cho, J.-Y.; Jeon, J.Y.; Koh, Y.G.; Kim, Y.-M.; Kim, H.-J.; Park, M.; Um, H.-S.; Kim, Chan |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 31 (2010), 1, S. 65-71, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-0029-1239523 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201004004046 |
Quelle: | BISp |
Abstract
The purpose of this study was to test the hypothesis that the ACE DD genotype is unfavorably associated with the ultimate power-oriented performance. To test the hypothesis we recruited a total of 848 subjects including 55 international level power-oriented athletes (High-performance), 100 national level power-oriented athletes (Mid-performance) and 693 healthy controls (Control) in Korea. Then the distributions of ACE polymorphism throughout these groups were analyzed. As a result, there was a gradual decrease of frequencies of the DD genotype with advancing levels of performance (Control vs. Mid-performance vs. High-performance = 17.2% vs. 10.0% vs. 5.5%, p = 0.002). Also, the frequencies of D allele decreased gradually with advancing levels of performance (Control vs. Mid-performance vs. High-performance = 42.6% vs. 35.0% vs. 30.9%, p < 0.01). Therefore, power-oriented athletes at the top level had a markedly diminished frequency of the DD genotype and the D allele. This finding gave 3.83 times lower probability of success in power-oriented sports for individuals with the DD genotype than those with the II+ID genotype. In conclusion, these results indicate that Korean power-oriented athletes with a lower frequency of the DD genotype had a lower probability of success in power-oriented sports. Verf.-Referat