Aerobic exercise is safe and effective in systemic sclerosis
Deutscher übersetzter Titel: | Aerobes Training bei systemischer Sklerose ist sicher und effektiv |
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Autor: | Oliveira, N.C.; Santos Sabbag, L.M. dos; Sá Pinto, A.L. de; Borges, C.L.; Lima, F.R. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 30 (2009), 10, S. 728-732, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-0029-1224180 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU200912006565 |
Quelle: | BISp |
Abstract
Several studies have established that systemic sclerosis patients have a reduced exercise capacity when compared to healthy individuals. It is relevant to evaluate whether aerobic exercise in systemic sclerosis patients is a safe and effective intervention to improve aerobic capacity. Seven patients without pulmonary impairment and seven healthy controls were enrolled in an 8-week program consisting of moderate intensity aerobic exercise. Patients and controls had a significant improvement in peak oxygen consumption (19.72 +/- 3.51 vs. 22.27 +/- 2.53 and 22.94 +/- 4.70 vs. 24.55 +/- 3.00, respectively, p=0.006), but difference between groups was not statistically significant (p=0.149). This finding was reinforced by the fact that at the end of the study both groups were able to perform a significantly higher exercise intensity when compared to baseline, as measured by peak blood lactate (1.43 +/- 0.51 vs. 1.84 +/- 0.33 and 1.11 +/- 0.45 vs. 1.59 +/- 0.25, respectively, p=0.01). Patients improved the peak exercise oxygen saturation comparing to the baseline (84.14 +/- 9.86 vs. 90.29 +/- 5.09, p=0.048). Rodnan score was similar before and after the intervention (15.84 +/- 7.84 vs.12.71 +/- 4.31, p=0.0855). Digital ulcers and Raynaud's phenomenon remained stable. Our data support the notion that improving aerobic capacity is a feasible goal in systemic sclerosis management. The long term benefit of this intervention needs to be determined in large prospective studies. Verf.-Referat