Vibrational spectroscopic study of salbutamol hemisulphate
Gespeichert in:
Deutscher übersetzter Titel: | Vibrierende spektroskopische Untersuchung von Salbutamol Hemisulfat |
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Autor: | Ali, H.R.H.; Edwards, H.G.M.; Kendrick, J.; Scowen, I.J. |
Erschienen in: | Drug testing and analysis |
Veröffentlicht: | 1 (2009), 1, S. 51-56, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 1942-7603, 1942-7611 |
DOI: | 10.1002/dta.8 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU200904002092 |
Quelle: | BISp |
Abstract
Salbutamol hemisulphate is a relatively selective 2-adrenergic agonist and is used as a bronchodilator. In this work, we present a detailed vibrational spectroscopic investigation of salbutamol hemisulphate using mid-infrared and near-infrared Fourier-transform (NIR-FT) Raman spectroscopies. These data are supported by quantum chemical calculations, which allow us to characterise the vibrational spectra of this compound reasonably. As such, this study could be viable for examining the way in which this drug interacts with its target molecules. Verf.-Referat