Lymphocyte and cytokines after short periods of exercise
Deutscher übersetzter Titel: | Lymphozyten und Zytokine nach kurzen Perioden körperlicher Aktivität |
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Autor: | Prestes, J.; Ferreira, C.K. de O.; Dias, R.; Frollini, A.B.; Donatto, F.F.; Cury-Boaventura, M.F.; Guereschi, M.G.; Pithon-Curi, T.C.; Verlengia, R.; Palanch, A.C.; Curi, R.; Cavaglieri, C.R. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 29 (2008), 12, S. 1010-1014, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2008-1038737 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU200901000471 |
Quelle: | BISp |
Abstract
The purpose of this study was to verify the effects of short periods of exercise of different intensity on lymphocyte function and cytokines. Thirty Wistar rats, 2 months old, were used. They were divided into five groups of six rats: a sedentary control group; a group exercised for 5 minutes at low intensity (5 L); a group exercised for 15 minutes at low intensity (15 L); and groups exercised at moderate intensity (additional load of 5 % of body weight) for 5 minutes (5 M) or for 15 minutes (15 M). The parameters measured were: total leukocytes, neutrophils, lymphocytes, monocytes, lymphocytes from lymph nodes, serum cytokines (IL-2, IL-6 and TNF-α), lymphocyte mitochondrial transmembrane potential, viability and DNA fragmentation. ANOVA two way followed by Tukey's post hoc test (p ≤ 0.05) was used. The exercised groups exhibited a significant increase in total leukocytes, tissue and circulating lymphocytes in comparison with the control group. There was a significant decrease in lymphocyte viability and decrease in DNA fragmentation for the 15 M group when compared with the control. There was a decrease in the level TNF-α in the 5 M and 15 M groups. Short-term, low- and moderate-intensity exercise may be considered for sedentary individuals beginning to exercise, since no deleterious alterations were observed in lymphocyte function. Verf.-Referat