Protective effect of sesamin administration on exercise-induced lipid peroxidation
Gespeichert in:
| Deutscher übersetzter Titel: | Schutzwirkung der Sesamgabe auf die durch Muskelarbeit bedingte Lipidperoxidation |
|---|---|
| Autor: | Ikeda, T.; Nishijima, Y.; Shibata, H.; Kiso, Y.; Ohnuki, K.; Fushiki, T.; Moritani, T. |
| Erschienen in: | International journal of sports medicine |
| Veröffentlicht: | 24 (2003), 7, S. 530-534, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
| Sprache: | Englisch |
| ISSN: | 0172-4622, 1439-3964 |
| DOI: | 10.1055/s-2003-42010 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU200411002981 |
| Quelle: | BISp |
Abstract
To investigate the mechanism of antioxidative effects of sesamin in vivo, 32 male ddY mice were administered with 10 mg/kg or 100 mg/kg of sesamin (S10, S100), 100 mg/kg of vitamin E (VE100) or control sample (C). They were subjected to 30 min of swimming exercise 2 h after the sample administration by using a new forced-swimming apparatus, i. e. an adjustable-current swimming pool. Exercise resulted in a significant increase in plasma lipid peroxides (LPO) in C and VE100 (p<0.01), but not in S10 and S100. S100 showed significantly higher total glutathione peroxidase activity and glutathione S-transferase activity in liver compared to C (p<0.05). In conclusion, sesamin may enhance LPO degradation in the liver resulting in the strong protective effects against exercise-induced plasma lipid peroxidation. Verf.-Referat