Identical twins are discordant for markers of eccentric exercise-induced muscle damage
Deutscher übersetzter Titel: | Identische Zwillinge sind gegensätzlich in Bezug auf Markern für durch exzentrische Muskelarbeit verursachte Muskelschädigung |
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Autor: | Gulbin, J.P.; Gaffney, P.T. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 23 (2002), 7, S. 471-476, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2002-35076 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU200407001935 |
Quelle: | BISp |
Abstract des Autors
This study investigated whether the variability observed in the markers of exercise-induced muscle damage (EIMD) has a genetic etiology. Sixteen pairs of identical twins performed 24 maximal eccentric contractions (24MAX) using the elbow flexors. EIMD indicators were measured pre-24MAX and three days post-24MAX and included: post-exercise force deficit, maximal isometric force (ISO), plasma creatine kinase (CK), myoglobin (Mb), and joint range of motion. Force-time curves were recorded throughout the 24MAX. Twin siblings were alike for pre-exercise ISO (intraclass R=0.89) and CK (R=0.76) (p<0.001), but were discordant for post-exercise force deficit (R=0.29), CK (R=0.15), and Mb (R=0.17) (p>0.05). In comparison with individuals minimally affected by the 24MAX, those who experienced the greatest force deficit 3 days post-exercise (> 50 %) were characterised by the greater application of eccentric force at longer muscle lengths (23.1 % vs 17.3 %) (p<0.05). This study demonstrates that twins do not experience the same level of EIMD following identical exercise bouts. This suggests that the individual variability following high-force eccentric exercise cannot be attributed to genetic differences, refuting the idea that an inherited subclinical predisposition is responsible. From these results, a potential mechanism for the repeated bout effect is discussed. Verf.-Referat