Effect of an intensive exercise of short duration on the expression of TNF-alpha and receptor TNF-R1 (sTNF) in the blood serum
Gespeichert in:
| Deutscher übersetzter Titel: | Auswirkungen eines kurzfristigen intensiven Trainings auf die Darstellung von TNF-alpha und Receptor TNF-R1 (sTNF) in den Serumwerten |
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| Autor: | Monkiewicz, M.; Kuliczkowski, K.; Zagrobelny, Z. |
| Erschienen in: | Medicina dello sport |
| Veröffentlicht: | 54 (2001), 4, S. 319-323, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
| Sprache: | Englisch |
| ISSN: | 0025-7826, 1827-1863 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU200210003017 |
| Quelle: | BISp |
Abstract
A group of subjects performed an intensive progressive "vita maxima" test of short duration. The samples of venous blood were taken before and immediately post-exercise. The levels of TNF-a and its receptor TNF-R1 in the blood serum were measured using the ELISA method (R&D Systems, UK). The mean work output of 215.6 kJ resulted in statistically significant increase in levels of TNF-alpha (p=0.000001) and TNF-R1 (p=0.0003) in the blood serum. It seems that serum TNF-R1 after the proteolytic shedding from the cell membrane is an effective inhibitor of apoptosis induced by the TNF-alpha production stimulated by an intensive physical exercise. Verf.-Referat