Acute intensive interval training and in vitro T-lymphocyte function
Deutscher übersetzter Titel: | Akutes intensives Intervalltraining und die Funktion der T-Lymphozyten in vitro |
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Autor: | Hinton, J.R.; Rowbottom, D.G.; Keast, D.; Morton, A.R. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 18 (1997), 2, S. 130-135, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2007-972608 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199703203197 |
Quelle: | BISp |
Abstract des Autors
Five male endurance-trained runners completed an interval running session of 15x1-min intervals at 95% VO2max. Venous blood samples were collected pre-exercise and then immediately, 30- and 60-minutes post-exercise. The response of cultures of total lymphocytes to mitogen (phytohaemagglutinin) were significantly reduced immediately after exercise, but returned to resting levels by 30-min of recovery. Conversely, the mitogen response of cultures of pure T-lymphocytes (CD4+ and CD8+ cells), separated using a magnetic separation technique, showed no significant change during the exercise and recovery periods. These data showed directly that there was no apparent change in the functional capability of T-lymphocytes following an intensive interval training session. Furthermore, there were significant changes in the composition of the total lymphocyte cultures immediately post-exercise; increased numbers of natural killer (NK) cells (CD56+) and T-suppressor cells (CD8+) and decreased numbers of T-helper cells (CD4+). There were also significant correlations between total mitogen response and the composition of the cultured lymphocytes. These data indicated that the large increases in NK cells, relative to T-cells, following intensive exercise, were the most likely cause of the reduced mitogen response of total lymphocyte cultures. Verf.-Referat