The effect of oral Coenzyme Q10 on the exercise tolerance of middle-aged, untrained men

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Deutscher übersetzter Titel:Auswirkung von Coenzym Q10 auf die koerperliche Belastbarkeit von untrainierten Maennern im mittleren Lebensalter
Autor:Porter, D.A.; Costill, D.L.; Zachwieja, J.J.; Krzeminski, K.; Fink, W.J.; Wagner, E.; Folkers, K.
Erschienen in:International journal of sports medicine
Veröffentlicht:16 (1995), 7, S. 421-427, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:0172-4622, 1439-3964
DOI:10.1055/s-2007-973031
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Erfassungsnummer:PU199510103456
Quelle:BISp

Abstract des Autors

In order to determine the effect of oral Coenzyme Q10 (CoQ10) dosing on exercise capacity, 15 middle-aged men (44.7 +/- 2.0 years) received either CoQ10 (150 mg/day x 2 months-Q10 GRP) or placebo (2 months-CON GRP). Blood CoQ10 levels increased during the treatment in the Q10 GRP and were unchanged in the CON GRP. Similarly, the subjective perception of vigor (visual analog scale 1-10 where, 10 = very energetic, and 0 = very, very unenergetic) increased in the Q10 GRP. However, maximal oxygen consumption and lactate threshold, as measured on the cycle ergometer, were unchanged as a result of the CoQ10 treatment, neither forearm oxygen uptake, nor forearm blood flow was found to be affected by the CoQ10. Although lactate release during hand-grip testing tended to decrease in the Q10 GRP this was not significant. It can be concluded that short-term (2 months) oral dosing with CoQ10 increases circulating blood levels of CoQ10 and the subjective perceived level of vigor in middle-aged men. However, short-term dosing does not improve aerobic capacity or forearm exercise metabolism as measured in this investigation. Verf.-Referat